1 Result for "

2653339-26-3

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "2653339-26-3" in MCE Product Catalog:

Cat. No.: HY-152146
CAS No.: 2653339-26-3
Target:  

Apoptosis FGFR HDAC

Research Areas:  

Cancer

HDAC-IN-50 is a potent and orally active FGFR and HDAC dual inhibitor with IC50 values of 0.18, 1.2, 0.46, 1.4, 1.3, 1.6, 2.6, 13 nM for FGFR1, FGFR2, FGFR3, FGFR4, HDAC1, HDAC2, HDAC6, HDAC8, respectively. HDAC-IN-50 induces Apoptosis and cell cycle arrest at G0/G1 phase. HDAC-IN-50 decreases the expression of pFGFR1, pERK, pSTAT3. HDAC-IN-50 shows anti-tumor activity .
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