1 Result for "

2737222-94-3

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "2737222-94-3" in MCE Product Catalog:

Cat. No.: HY-168487
CAS No.: 2737222-94-3
Target:  

PROTACs WDR5

Research Areas:  

Cancer

PROTAC WDR5 degrader 1 is a heterobifunctional WDR5 PROTAC degrader with a DC50 value of 53 nM and a Kd value of 18 nM, exhibiting selective WDR5 degradation activity and cell permeability. PROTAC WDR5 degrader 1 induces proliferation defects in leukemia cells, with enhanced efficacy in cells overexpressing VHL. PROTAC WDR5 degrader 1 is applicable to research related to acute myeloid leukemia .
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