1 Result for "

2750570-55-7

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "2750570-55-7" in MCE Product Catalog:

Cat. No.: HY-148278
CAS No.: 2750570-55-7
Purity:  99.83%
Target:  

SOS1 Ras

Research Areas:  

Cancer

BI-0474 is a potent KRAS G12C inhibitor with an IC50 value of 7.0 nM for the GDP-KRAS::SOS1 protein-protein interaction. BI-0474 exhibits good anti-proliferative activity against NCI-H358 cells carrying the G12C mutation. BI-0474 also shows good anti-tumour activity in non-small cell lung cancer xenograft models .
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