1 Result for "

2756846-09-8

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "2756846-09-8" in MCE Product Catalog:

Cat. No.: HY-145858
CAS No.: 2756846-09-8
Target:  

Ferroptosis

Research Areas:  

Cancer

Chalcones A-N-5 is a trihydroxy chalcone derivative compound. Chalcones A-N-5 doesn’t show cytotoxicity at the concentration lower than 100 µM (with IC50 > 1 mM), but has a significant effect on promoting cell proliferation. Chalcones A-N-5 potentially promotes neuronal cell growth in the damaged brain tissue. Chalcones A-N-5 also inhibits ferroptosis induced by RSL or erastin and reduces the lipid peroxidation levels induced by Aβ1-42 protein aggregation. Chalcones A-N-5 is a promising molecular skeleton candidate for further development of lead compound for in vivo test to research AD .
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