1 Result for "

2761881-65-4

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "2761881-65-4" in MCE Product Catalog:

Cat. No.: HY-175206
CAS No.: 2761881-65-4
Target:  

P-glycoprotein

Research Areas:  

Cancer

P-gp-IN-30 (Compound 13) is a P-glycoprotein (P-gp) inhibitor by targeting YB-1. P-gp-IN-30 significantly enhances sensitivity to Paclitaxel by reducing total YB-1 and nucleus YB-1 protein expression, inhibiting the expression and function of downstream P-gp, further suppressing the efflux rate of Paclitaxel. P-gp-IN-30 potently inhibits tumor growth in A549/Taxol xenografts mice model with combination of Paclitaxel (HY-B0015). P-gp-IN-30 can be used for non-small cell lung cancer (NSCLC) research .
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