1 Result for "

2856391-46-1

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "2856391-46-1" in MCE Product Catalog:

Cat. No.: HY-168081
CAS No.: 2856391-46-1
Target:  

PD-1/PD-L1

Research Areas:  

Cancer

PD-1/PD-L1-IN-52 (Compound III-5) is an orally active PD-1/PD-L1 inhibitor that blocks the interaction between PD-1 and PD-L1, with an IC50 of 109.9 nM. PD-1/PD-L1-IN-52 exhibits antitumor activity in a C57BL/6 mouse xenograft model implanted with human PD-1-expressing MC38 colon cancer cells, with a TGI of 49.6% .
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