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PD-1/PD-L1-IN-52

PD-1/PD-L1-IN-52 (Compound III-5) is an orally active PD-1/PD-L1 inhibitor that blocks the interaction between PD-1 and PD-L1, with an IC50 of 109.9 nM. PD-1/PD-L1-IN-52 exhibits antitumor activity in a C57BL/6 mouse xenograft model implanted with human PD-1-expressing MC38 colon cancer cells, with a TGI of 49.6%.

For research use only. We do not sell to patients.

  • CAS No.: 2856391-46-1
  • Formula: C45H52ClN7O9
  • Molecular Weight:870.39
  • Storage:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • PD-1/PD-L1-IN-52 Chemical Structure
    PD-1/PD-L1-IN-52 Chemical Structure
CAS No.: 2856391-46-1
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  • PD-1/PD-L1-IN-52 Chemical Structure
    PD-1/PD-L1-IN-52 Chemical Structure
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  • PD-1/PD-L1-IN-52