1 Result for "

2902679-42-7

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "2902679-42-7" in MCE Product Catalog:

Cat. No.: HY-173559
CAS No.: 2902679-42-7
Target:  

Androgen Receptor

Research Areas:  

Cancer

AR antagonist 12 (compound 20i) is an orally active androgen receptor antagonist wiith IC50 values of 119.3 μM and 98.2 μM for wt-AR and AR-F877L,respectively. AR antagonist 12 induces a dose-dependent and time-dependent reduction in AR, AR-V7, and PSA protein levels. AR antagonist 1 shows anticancer activuty and can be used for the study of Enzalutamide (HY-70002)-resistant Prostate cancer .
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