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29080-58-8

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7,3',4'-Tri-O-methylluteolin
7,3',4'-Tri-O-methylluteolin
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Cat. No.: HY-N7012
CAS No.: 29080-58-8
Synonyms: 5-Hydroxy-3',4',7-trimethoxyflavone
Category:  

Flavonoids Monophenols Flavones Labiatae Phenols Plants Disease Research Fields Swartzia polyphylla DC. Inflammation/Immunology

Target:  

Lipoxygenase TNF Receptor Interleukin Related COX Fungal Parasite Apoptosis

7,3',4'-Tri-O-methylluteolin (5-Hydroxy-3',4',7-trimethoxyflavone) is a flavonoid with multiple biological activities. 7,3',4'-Tri-O-methylluteolin inhibits soybean lipoxygenase (LOX), with an IC50 value of 23.97 µg/mL. 7,3',4'-Tri-O-methylluteolin possesses anti-inflammatory effects in Lipopolysaccharides (HY-D1056) (LPS)-induced RAW 264.7 macrophages. 7,3',4'-Tri-O-methylluteolin inhibits the binding of MDM2 with p53 and induces apoptosis in MCF-7 breast cancer cells. 7,3',4'-Tri-O-methylluteolin also has antioxidant, antifungal and antitrypanosomal activities .
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