1 Result for "

2919995-09-6

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "2919995-09-6" in MCE Product Catalog:

Cat. No.: HY-168586
CAS No.: 2919995-09-6
Target:  

PROTACs IRAK IKZF Family

Research Areas:  

Cancer

PROTAC IRAK4 degrader-12 is an orally active IRAK4 PROTAC degrader with a DC50 of 4.87 nM in K562 IRAK4-HiBiT cells. PROTAC IRAK4 degrader-12 induces protein degradation of IRAK4, IKZF1 and IKZF3. It inhibits the proliferation of diffuse large B-cell lymphoma cells. It suppresses tumor growth in mouse xenograft models of lymphoma cells. PROTAC IRAK4 degrader-12 can be used for the research of B-cell lymphoma and diffuse large B-cell lymphoma .
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