1 Result for "

3025012-68-1

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "3025012-68-1" in MCE Product Catalog:

Cat. No.: HY-161694
CAS No.: 3025012-68-1
Target:  

DNA Methyltransferase

Research Areas:  

Cancer

DNMT1-IN-3 (compound 7t-S) is an effective DNA methyltransferase 1 (DNMT1) inhibitor with an IC50 value of 0.777 μM and a KD value of 0.183 μM. DNMT1-IN-3 can bind to the methyl donor S-adenosyl-l-methionine (SAM) site in DNMT1. DNMT1-IN-3 can inhibit cell proliferation in K562 cells by inducing cells apoptosis and arresting cell cycle at G0 / G1 phase, which has the potential to be used for the research of hematologic tumor .
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