1 Result for "

3035323-39-5

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "3035323-39-5" in MCE Product Catalog:

Cat. No.: HY-158038
CAS No.: 3035323-39-5
Target:  

Aurora Kinase Mitosis

Research Areas:  

Cancer

AurkA allosteric-IN-1 (compound 6h) is an Aurora A (AurkA) inhibitor (IC50: 6.50 μM) that inhibits the catalytic activity and non-catalytic functions of Aurora A. Aurora A regulates the assembly of the bipolar mitotic spindle and the fidelity of chromosome segregation during mitosis and has non-catalytic functions. AurkA allosteric-IN-1 blocks the interaction of AurkA with the activator TPX2 by binding to the Y pocket of AurkA .
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