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3037776-72-7

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1 Results for "3037776-72-7" in MCE Product Catalog:

Cat. No.: HY-180925
CAS No.: 3037776-72-7
Target:  

PROTACs Bcr-Abl

Research Areas:  

Cancer

Leu-PEG1-Dasa is a potent BCR-ABL PROTAC degrader with a DC50 of 0.48 nM. Leu-PEG1-Dasa uses a single amino acid as the E3 ligand and belongs to a mini-PROTAC, functioning through the N-terminal canonical pathway. Leu-PEG1-Dasa exhibits potent anti-proliferative activity against K562 cells. Leu-PEG1-Dasa can be used for the study of chronic myeloid leukemia (CML) .
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