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3047610-96-5

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "3047610-96-5" in MCE Product Catalog:

Cat. No.: HY-161663
CAS No.: 3047610-96-5
Research Areas:  

Cardiovascular Disease

Phosphodiesterase-IN-2 (Compound C7) is a selective, orally active inhibitor for phosphodiesterase 10A (PDE10A), with an IC50 of 11.9 nM. Phosphodiesterase-IN-2 improves the stability of liver microsomes, and lowers BBB permeability. Phosphodiesterase-IN-2 exhibits good pharmacokinetic characters, and attenuates isoprenaline (HY-108353)-induced cardiac hypertrophic in mouse models .
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