1 Result for "

3066008-42-9

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "3066008-42-9" in MCE Product Catalog:

Cat. No.: HY-186117
CAS No.: 3066008-42-9
Target:  

YAP PROTACs

Research Areas:  

Cancer

KG-FP-003 is a highly potent, selective, and durable TEAD PROTAC degrader (TEAD1 DC50 = 6 ± 4 nM, TEAD2 DC50 = 68 ± 15 nM, TEAD3 DC50 = 12 ± 5 nM, TEAD4 DC50 = 7 ± 5 nM). KG-FP-003 promotes ubiquitination and degradation of TEAD. KG-FP-003 exhibits anticancer activity against mesothelioma and ovarian cancer .
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