1 Result for "

3077918-44-3

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "3077918-44-3" in MCE Product Catalog:

Cat. No.: HY-178728
CAS No.: 3077918-44-3
Research Areas:  

Infection

BION106 is a dihydrofolate reductasethymidylate synthase (DHFR-TS) PROTAC degrader. BION106 exhibits extremely strong anti-malarial activity with a Ki and toxicity of 2.68 nM and 0.2 μM against Plasmodium falciparum, and > 100 μM and 44.2 μM in mammalian cells. BION106 can be used for the study of antimalarial parasites (Blue: Idasanutlin ligand (HY-15676); Pink: DHFR-TS ligand (HY-153007); Black: Linker (HY-W021401)) .
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