1 Result for "

3078322-88-7

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "3078322-88-7" in MCE Product Catalog:

Cat. No.: HY-176702
CAS No.: 3078322-88-7
Research Areas:  

Cancer

PRMT5-MTA-IN-5 (Compound 7) is an orally active, irreversible PRMT5-MTA complex (PRMT5•MTA) inhibitor (IC50=1.15 nM). PRMT5-MTA-IN-5 blocks arginine methylation and inhibits ribosomal RNA processing and cell cycle-related protein expression. PRMT5-MTA-IN-5 potently inhibits proliferation in MTAP-deficient tumor cells. PRMT5-MTA-IN-5 is promising for research of MTAP-deficient solid tumors, such as liver, breast, and pancreatic cancers .
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