1 Result for "

3081681-34-4

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "3081681-34-4" in MCE Product Catalog:

Cat. No.: HY-173397
CAS No.: 3081681-34-4
Research Areas:  

Metabolic Disease

β-Glucuronidase-IN-3 (Compound 49) is a covalent allosteric β-glucuronidase inhibitor. β-Glucuronidase-IN-3 has potent inhibitory activity against Escherichia coli β-glucuronidase (EcGUS) (IC50: 12.9 nM). β-Glucuronidase-IN-3 exerts its inhibitory effect by reversibly covalently modifying the cysteine residues (Cys28, Cys443, and Cys197) of EcGUS. β-Glucuronidase-IN-3 can be used in the study of intestinal microbiota-related diseases, especially to alleviate the toxic side effects of Irinotecan (HY-16562) and nonsteroidal anti-inflammatory drugs (NSAIDs) .
loading...
    loading...