1 Result for "

3087335-24-5

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "3087335-24-5" in MCE Product Catalog:

Cat. No.: HY-175684
CAS No.: 3087335-24-5
Target:  

JAK STAT Apoptosis

Research Areas:  

Cancer

JAK2-IN-14 is an orally active JAK2 inhibitor with an IC50 of 2 nM. JAK2-IN-14 demonstrates 89.5-, 80.5-, and 51-fold selectivity over JAK1, JAK3, and TYK2, respectively. JAK2-IN-14 inhibits STAT5 signaling pathway. JAK2-IN-14 causes tumor cell cycle arrest and apoptosis. JAK2-IN-14 can used for the study of myeloproliferative neoplasms (MPNs) .
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