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3104354-58-4

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "3104354-58-4" in MCE Product Catalog:

Cat. No.: HY-183688
CAS No.: 3104354-58-4
Research Areas:  

Infection

MptpB-IN-3 is a selective inhibitor of Mycobacterium tuberculosis protein tyrosine phosphatase B (MptpB) with an IC50 of 0.19 μM. MptpB-IN-3 blocks MptpB-mediated inhibition of the macrophage MAPK pathway and restores the phosphorylation levels of Erk1/2 and p38. MptpB-IN-3 exhibits direct anti-tuberculosis activity against Mycobacterium tuberculosis and reduces the Mycobacterium tuberculosis load in mouse macrophages. MptpB-IN-3 can be used for tuberculosis research .
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