1 Result for "

3106363-91-8

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "3106363-91-8" in MCE Product Catalog:

Cat. No.: HY-170434
CAS No.: 3106363-91-8
Research Areas:  

Cancer

Bfl-1-IN-6 is an orally active BFL1 inhibitor with an IC50 of 19 nM. Bfl-1-IN-6 selectively binds covalently to BFL1, stabilizes the protein and displaces BIM from BFL1, thereby inducing apoptosis activity. Bfl-1-IN-6 stabilizes BFL1 protein, activates cleaved caspase 3, and exhibits antitumor activity in mouse models. Bfl-1-IN-6 can be used for the research of hematological malignancies .
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