1 Result for "

3114520-65-6

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "3114520-65-6" in MCE Product Catalog:

Cat. No.: HY-183710
CAS No.: 3114520-65-6
Research Areas:  

Cancer

CDK9-IN-50 is a selective and orally active CDK9 inhibitor with an IC50 of 2.2 nM. CDK9-IN-50 targets a distinct CDK9-specific subpocket to disrupt RNA polymerase II Ser2 phosphorylation and downregulate short-lived oncoproteins, including AR-V7 and Myc. CDK9-IN-50 exhibits antiproliferative activity against cancer cells, induces apoptosis and induces tumor growth inhibition in CRPC orthotopic mice models. CDK9-IN-50 can be used for the research of cancer, such as prostate cancer .
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