1 Result for "

3126555-64-1

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "3126555-64-1" in MCE Product Catalog:

Cat. No.: HY-176230
CAS No.: 3126555-64-1
Target:  

DNA Methyltransferase

Research Areas:  

Cancer

DNMT-IN-5 is a stable and efficient DNA methyltransferase (DNMT) inhibitor with high stability and high activity with an IC50 of 0.78 nM. DNMT-IN-5 exhibits sub-micromolar DNMT3A inhibitory activity, upregulates the expression of DNMT-targeted genes, impairs cell proliferation, and triggers a critical cell cycle arrest. DNMT-IN-5 can be used for the study of p53-depleted colorectal cancer .
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