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444914-19-6

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "444914-19-6" in MCE Product Catalog:

Cat. No.: HY-155851
CAS No.: 444914-19-6
Lepadin E is a significantly cytotoxic ferroptosis inducer that induces iron death through the classical p53-SLC7A11-GPX4 pathway. Lepadin E promoted p53 expression, decreases SLC7A11 and GPX4 levels, and leads to increased ROS and lipid peroxide production, and upregulated ACSL4 expression, thus causes cell death. Lepadin E has significant antitumor effect .
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