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5-FU (Standard)

" in MedChemExpress (MCE) Product Catalog:

8

Inhibitors & Agonists

2

Natural
Products

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-90006R
    5-Fluorouracil (Standard)
    1 Publications Verification

    5-FU (Standard)

    		 Reference Standards Exosomes Nucleoside Antimetabolite/Analog HIV Apoptosis Endogenous Metabolite Cancer
    5-Fluorouracil (Standard) is the analytical standard of 5-Fluorouracil. This product is intended for research and analytical applications. 5-Fluorouracil (5-FU) is an analogue of uracil and a potent antitumor agent. 5-Fluorouracil affects pyrimidine synthesis by inhibiting thymidylate synthetase thus depleting intracellular dTTP pools. 5-Fluorouracil induces apoptosis and can be used as a chemical sensitizer . 5-Fluorouracil also inhibits HIV .
    5-Fluorouracil (Standard)
  • HY-B0016R
    Capecitabine (Standard)

    		Reference Standards DNA/RNA Synthesis Nucleoside Antimetabolite/Analog Apoptosis Cancer
    Capecitabine (Standard) is the analytical standard of Capecitabine. This product is intended for research and analytical applications. Capecitabine is an oral proagent that is converted to its active metabolite, 5-FU, by thymidine phosphorylase.
    Capecitabine (Standard)
  • HY-W010450R
    Thymine (Standard)

    		Reference Standards Endogenous Metabolite Metabolic Disease Cancer
    Thymine (Standard) is the analytical standard of Thymine. This product is intended for research and analytical applications. Thymine is one of the four nucleobases in the nucleic acid of DNA and can be a target for actions of 5-fluorouracil (5-FU) in cancer treatment, with a Km of 2.3 μM.
    Thymine (Standard)
  • HY-17400R
    Tegafur (Standard)

    FT 207 (Standard); NSC 148958 (Standard)

    		 Reference Standards Nucleoside Antimetabolite/Analog Cancer
    Tegafur (Standard) is the analytical standard of Tegafur. This product is intended for research and analytical applications. Tegafur (FT 207; NSC 148958) is a chemotherapeutic 5-FU proagent used in the treatment of cancers; is a component of tegafur-uracil.
    Tegafur (Standard)
  • HY-B0021R
    Doxifluridine (Standard)

    Ro 21-9738 (Standard); 5-Fluoro-5'-deoxyuridine (Standard); 5'-DFUR (Standard)

    		 Thymidylate Synthase Reference Standards Cancer
    Doxifluridine (Standard) is the analytical standard of Doxifluridine. This product is intended for research and analytical applications. Doxifluridine has anticancer activity. Doxifluidine is a 5-FU prodrug. Doxifluridine is a thymidine synthase inhibitor. Doxifluridine can enhance tumor inhibition by synergizing with a variety of drugs .
    Doxifluridine (Standard)
  • HY-106406R
    Benzylacyclouridine (Standard)

    BAU (Standard); 5-Benzylacyclouridine (Standard)

    		 Drug Derivative Reference Standards Cancer
    Benzylacyclouridine (Standard) is the analytical standard of Benzylacyclouridine. This product is intended for research and analytical applications. Benzylacyclouridine (BAU) is a potent and specific inhibitor of uridine phosphorylase, the first enzyme in the catabolism of uridine. Benzylacyclouridine can modulate the cytotoxic side effects of 5-fluorouracil (5-FU) and its derivatives .
    Benzylacyclouridine (Standard)
  • HY-101467R
    Trilaciclib (Standard)

    G1T28 (Standard)

    		 CDK Reference Standards Cancer
    Trilaciclib (Standard) is the analytical standard of Trilaciclib (HY-101467). This product is intended for research and analytical applications. Trilaciclib (G1T28) is an orally active CDK4/6 inhibitor with IC50 values of 1 nM and 4 nM for CDK4 and CDK6, respectively. . Trilaciclib can effectively inhibit tumor cell proliferation and reduce the hematological toxicity caused by chemotherapy. Trilaciclib attenuates apoptosis and myelosuppression induced by 5FU (HY-90006) chemotherapy .
    Trilaciclib (Standard)
  • HY-103363R
    SB-328437 (Standard)

    		Reference Standards CCR Thymidylate Synthase Inflammation/Immunology Cancer
    SB-328437 (Standard) is the analytical standard of SB-328437 (HY-103363). This product is intended for research and analytical applications. SB-328437 is a potent, selective non-peptide CCR3 antagonist with an IC50 of 4.5 nM. SB-328437 can inhibit eosinophil migration induced by eotaxin, eotaxin-2, and monocyte chemotactic protein-4. In addition, SB-328437 can sensitize 5-FU (HY-90006)-resistant gastric cancer cells. SB-328437 can also reduce the recruitment of neutrophils to the lungs and pulmonary inflammation during acute inflammation. SB-328437 can be used in the research of inflammation-related diseases .
    SB-328437 (Standard)

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