65-71-4
65-71-4
Chemical Structure
Thymine
- CAS No.: 65-71-4
- Formula:C5H6N2O2
- Molecular Weight:126.11
IUPAC Name: 5-methylpyrimidine-2,4(1H,3H)-dione
InChIKey: RWQNBRDOKXIBIV-UHFFFAOYSA-N
SMILES: O=C1NC(C(C)=CN1)=O
Biological Activity: Thymine, one of the four bases of DNA, is a substrate for rat liver dihydropyrimidine dehydrogenase (DPD), with a Km value of 2.2 μM, Ki of 24 μM (using 5-FU as the DPD substrate), and a specific activity of 0.68 nmol/min/mg[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Thymine | 99.94% | Thymine, one of the four bases of DNA, is a substrate for rat liver dihydropyrimidine dehydrogenase (DPD), with a Km value of 2.2 μM, Ki of 24 μM (using 5-FU as the DPD substrate), and a specific activity of 0.68 nmol/min/mg. | ||||||||||||||||||||
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Thymine (Standard) | 99.99% | Thymine (Standard) is the analytical standard of Thymine. This product is intended for research and analytical applications. Thymine is one of the four nucleobases in the nucleic acid of DNA and can be a target for actions of 5-fluorouracil (5-FU) in cancer treatment, with a Km of 2.3 μM. | ||||||||||||||||||||
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Thymine-15N2,13C | 99.90% | Thymine-15N2,13C is the 13C and 15N labeled Thymine (HY-W010450). Thymine is one of the four nucleobases in the nucleic acid of DNA and can be a target for actions of 5-Fluorouracil (HY-90006) in cancer treatment, with a Km of 2.3 μM. | ||||||||||||||||||||
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Thymine-d4 | Thymine-d4 is the deuterium labeled Thymine. Thymine is one of the four nucleobases in the nucleic acid of DNA and can be a target for actions of 5-fluorouracil (5-FU) in cancer treatment, with a Km of 2.3 μM. | |||||||||||||||||||||
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Thymine-15N2 | Thymine-15N2 is the 15N labeled Thymine. Thymine is one of the four nucleobases in the nucleic acid of DNA and can be a target for actions of 5-fluorouracil (5-FU) in cancer treatment, with a Km of 2.3 μM. | |||||||||||||||||||||
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Thymine-13C5,15N,15N2 | Thymine-13C5,15N2 (5-Methyluacil-13C5,15N2) is 13C and 15N labeled Thymine. Thymine is one of the four nucleobases in the nucleic acid of DNA and can be a target for actions of 5-fluorouracil (5-FU) in cancer treatment, with a Km of 2.3 μM. | |||||||||||||||||||||
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Thymine-13C | Thymine-13C is the 13C labeled Thymine. Thymine is one of the four nucleobases in the nucleic acid of DNA and can be a target for actions of 5-fluorouracil (5-FU) in cancer treatment, with a Km of 2.3 μM. | |||||||||||||||||||||
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Thymine-d4-1 | 99.47% | Thymine-d4-1 is the deuterium labeled Thymine. Thymine is one of the four nucleobases in the nucleic acid of DNA and can be a target for actions of 5-fluorouracil (5-FU) in cancer treatment, with a Km of 2.3 μM. | ||||||||||||||||||||
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5-Fluorouracil | 99.87% | 5-Fluorouracil (5-FU) is an analogue of uracil and a potent antitumor agent. 5-Fluorouracil affects pyrimidine synthesis by inhibiting thymidylate synthetase thus depleting intracellular dTTP pools. 5-Fluorouracil induces apoptosis and can be used as a chemical sensitizer. 5-Fluorouracil also inhibits HIV. | ||||||||||||||||||||
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5-Fluorouracil-d1 | 99.9% | 5-Fluorouracil-d is the deuterium labeled 5-Fluorouracil. 5-Fluorouracil (5-FU) is an analogue of uracil and a potent antitumor agent. 5-Fluorouracil affects pyrimidine synthesis by inhibiting thymidylate synthetase thus depleting intracellular dTTP pools. 5-Fluorouracil induces apoptosis and can be used as a chemical sensitizer. 5-Fluorouracil also inhibits HIV. | ||||||||||||||||||||
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5-Fluorouracil-13C,15N2 | 5-Fluorouracil-13C,15N2 is the 13C and 15N labeled 5-Fluorouracil. 5-Fluorouracil (5-FU) is an analogue of uracil and a potent antitumor agent. 5-Fluorouracil affects pyrimidine synthesis by inhibiting thymidylate synthetase thus depleting intracellular dTTP pools. 5-Fluorouracil induces apoptosis and can be used as a chemical sensitizer. 5-Fluorouracil also inhibits HIV. | |||||||||||||||||||||
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5-Fluorouracil-13C4,15N2 | 5-Fluorouracil-13C4,15N2 is the 13C and 15N labeled 5-Fluorouracil. 5-Fluorouracil (5-FU) is an analogue of uracil and a potent antitumor agent. 5-Fluorouracil affects pyrimidine synthesis by inhibiting thymidylate synthetase thus depleting intracellular dTTP pools. 5-Fluorouracil induces apoptosis and can be used as a chemical sensitizer. 5-Fluorouracil also inhibits HIV. | |||||||||||||||||||||
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5-Chlorouracil | 99.50% | 5-Chlorouracil (Fluorouracil Impurity) is a biochemical reagent that can be used as a biological material or organic compound for life science related research. | ||||||||||||||||||||
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Uracil-d2 | 99.77% | Uracil-d2 is the deuterium labeled Uracil. Uracil is a common and naturally occurring pyrimidine derivative and one of the four nucleobases in the nucleic acid of RNA. | ||||||||||||||||||||
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Uracil-d1 | 99.96% | Uracil-d1 is the deuterium labeled Uracil. Uracil is a common and naturally occurring pyrimidine derivative and one of the four nucleobases in the nucleic acid of RNA. | ||||||||||||||||||||
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Uracil-d1-1 | Uracil-d1-1 is the deuterium labeled Uracil. Uracil is a common and naturally occurring pyrimidine derivative and one of the four nucleobases in the nucleic acid of RNA. | |||||||||||||||||||||
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5-Bromouracil | 99.99% | 5-Bromouracil is a biochemical reagent that can be used as a biological material or organic compound for life science related research. | ||||||||||||||||||||
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5-Iodouracil | 99.95% | 5-Iodouracil is an iodinated uracil pyrimidine base and a thymine analog. 5-Iodouracil exerts its lethal effect by substituting for thymine and being incorporated into phage DNA. 5-Iodouracil does not interfere with the host cell's transfer of thymine to progeny phages, nor does it alter lysis time or phage DNA content. 5-Iodouracil has no direct effect on phage particles, adsorption, or plating efficiency. Short oligonucleotide prodrugs containing 5-Fluoro and 5-Iodouracil are able to exert anticancer effects in a photoresponsive manner. | ||||||||||||||||||||
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5-Hydroxymethyluracil-d3 | 99% | 5-Hydroxymethyluracil-d3 is the deuterium labeled 5-Hydroxymethyluracil. 5-Hydroxymethyluracil is a product of oxidative DNA damage. 5-Hydroxymethyluracil can be used as a potential epigenetic mark enhancing or inhibiting transcription with bacterial RNA polymerase. | ||||||||||||||||||||
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5-Methylcytosine-d4 | 99% | 5-Methylcytosine-d4 is the deuterium labeled 5-Methylcytosine (HY-W008091). 5-Methylcytosine is a well-characterized DNA modification in prokaryotes and eukaryotes. 5-Methylcytosine forms symmetrical methylation on CpG dinucleotides in DNA, stabilizes tRNA/rRNA structure in RNA, and affects mRNA translation. 5-Methylcytosine can be oxidized to generate 5hmC, 5fC, and 5caC. 5-Methylcytosine can be used in epigenetics, developmental biology, and the study of diseases such as colorectal cancer and hepatocellular carcinoma. | ||||||||||||||||||||
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7-Methylxanthine-d33 | 99.31% | 7-Methylxanthine-d3 is deuterium labeled 7-Methylxanthine. 7-Methylxanthine, a methyl derivative of xanthine, is one of the purine components in urinary calculi. | ||||||||||||||||||||
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6-Amino-3-methylpyrimidine-2,4(1H,3H)-dione-d3 | 6-Amino-3-methylpyrimidine-2,4(1H,3H)-dione-d3 (6-Amino-3-methyluracil-d3) is the deuterium labeled 6-Amino-3-methylpyrimidine-2,4(1H,3H)-dione (HY-W038777). | |||||||||||||||||||||
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