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Cat. No.: HY-106406R

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Benzylacyclouridine (Standard)

(Synonyms: BAU (Standard); 5-Benzylacyclouridine (Standard))

Benzylacyclouridine (Standard) is the analytical standard of Benzylacyclouridine. This product is intended for research and analytical applications. Benzylacyclouridine (BAU) is a potent and specific inhibitor of uridine phosphorylase, the first enzyme in the catabolism of uridine. Benzylacyclouridine can modulate the cytotoxic side effects of 5-fluorouracil (5-FU) and its derivatives.

For research use only. We do not sell to patients.

CAS No.: 82857-69-0
Formula: C₁₄H₁₆N₂O₄
Molecular Weight:276.29

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Benzylacyclouridine (Standard) Chemical Structure

CAS No.: 82857-69-0

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Chemical Information
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Product Information

Information

Application

The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.

Chemical Information

CAS No. 82857-69-0
Molecular Weight 276.29
Formula C₁₄H₁₆N₂O₄
SMILES

OCCOCN(C(NC1=O)=O)C=C1CC2=CC=CC=C2
Synonyms

BAU (Standard); 5-Benzylacyclouridine (Standard)
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

References

[1]. Pizzorno G, et, al. Phase I clinical and pharmacological studies of benzylacyclouridine, a uridine phosphorylase inhibitor. Clin Cancer Res. 1998 May;4(5):1165-75. [Content Brief]

[2]. Monks A, et, al. Effect of 5-benzylacyclouridine, a potent inhibitor of uridine phosphorylase, on the metabolism of circulating uridine by the isolated rat liver. Biochem Pharmacol. 1983 Jul 1;32(13):2003-9. [Content Brief]

[3]. Roosild TP, et, al. Implications of the structure of human uridine phosphorylase 1 on the development of novel inhibitors for improving the therapeutic window of fluoropyrimidine chemotherapy. BMC Struct Biol. 2009 Mar 16;9:14. [Content Brief]

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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