1 Result for "

5XFAD/Rubicon KO mouse model

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "5XFAD/Rubicon KO mouse model" in MCE Product Catalog:

Cat. No.: HY-172941
Research Areas:  

Neurological Disease

VEN-02XX is an orally active and brain-permeable NLRP3 inhibitor. VEN-02XX inhibits the release of IL-1β and IL-18 (IC50 0.3 and 0.28 μM, respectively). VEN-02XX restores memory and cognition, inhibits microgliosis, and reduces neuroinflammation and tau pathology in the 5XFAD/Rubicon KO mouse model. VEN-02XX may be used in the study of Alzheimer's disease (AD) .
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