1 Result for "

717094-37-6

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "717094-37-6" in MCE Product Catalog:

Cat. No.: HY-175819
CAS No.: 717094-37-6
Target:  

Wee1 Apoptosis

Research Areas:  

Cancer

PD-166285 is a PKMYT1 inhibitor, with an IC50 value of 17 nM. PD166285 shows strong antiproliferative effects against CCNE1-amplified OVCAR3 cells (IC50 = 0.14 μM) and HCC1569 cells (IC50 = 0.21 μM). PD166285 induces apoptosis and arrests CCNE1-amplified HCC1569 cells at the G1/S phase of the cell cycle. PD166285 can be used for the research of PKMYT1-targeted therapies for CCNE1-amplified cancers .
loading...
    loading...