1 Result for "

788821-30-7

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "788821-30-7" in MCE Product Catalog:

Cat. No.: HY-167939
CAS No.: 788821-30-7
Target:  

Adrenergic Receptor

Research Areas:  

Inflammation/Immunology

(R)-Bambuterol is a β2-receptor agonist with anti-asthmatic and colitis-improving activity. (R)-Bambuterol is indicated for the treatment of asthma and chronic obstructive pulmonary disease and has the advantage of a once-daily dosing and a favorable side effect profile. (R)-Bambuterol significantly reduced disease severity in a mouse model of colitis, more effectively than (RS)-Bambuterol or (S)-Bambuterol. (R)-Bambuterol can significantly reduce the levels of inflammatory cytokines and reduce the infiltration of macrophages in mice with colitis. (R)-Bambuterol also increases β2-adrenoceptor levels and reduces the expression of IL-6, IL-17 and other related proteins in colon tissue in a dose-dependent manner .
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