1 Result for "

ACP-196 (Standard)

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "ACP-196 (Standard)" in MCE Product Catalog:

Cat. No.: HY-17600R
CAS No.: 1420477-60-6
Synonyms: ACP-196 (Standard)
Target:  

Reference Standards Btk

Research Areas:  

Cancer

Acalabrutinib (Standard) is the analytical standard of Acalabrutinib. This product is intended for research and analytical applications. Acalabrutinib (ACP-196) is an orally active, irreversible, and highly selective second-generation BTK inhibitor. Acalabrutinib binds covalently to Cys481 in the ATP-binding pocket of BTK. Acalabrutinib demonstrates potent on-target effects and efficacy in mouse models of chronic lymphocytic leukemia (CLL) . Acalabrutinib is a click chemistry reagent, itcontains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
loading...
    loading...