1 Result for "

AChE-IN-6

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "AChE-IN-6" in MCE Product Catalog:

Cat. No.: HY-144324
CAS No.: 2758788-95-1
Target:  

Cholinesterase (ChE)

Research Areas:  

Neurological Disease

AChE-IN-6 (Compound 12a) is an optimal multifunctional ligand with significant inhibition of AChE (EeAChE, IC50 = 0.20 μM; HuAChE, IC50 = 37.02 nM) and anti-Aβ activity (IC50 = 1.92 μM for self-induced Aβ1-42 aggregation; IC50 = 1.80 μM for disaggregation of Aβ1-42 fibrils; IC50 = 2.18 μM for Cu2+-induced Aβ1-42 aggregation; IC50 = 1.17 μM for disaggregation of Cu2+-induced Aβ1-42 fibrils). AChE-IN-6 has the potential for the research of Alzheimer's disease .
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