8 Results for "

ALK inhibitor1

" in MedChemExpress (MCE) Product Catalog:
Products (8)

8 Results for "ALK inhibitor1" in MCE Product Catalog:

1
1 Cited Publications
Cat. No.: HY-15357
CAS No.: 761436-81-1
Purity:  99.62%
Research Areas:  

Cancer

ALK inhibitor 1 (compound 17) is a potent pyrimidin ALK inhibitor. ALK inhibitor 1 is a potent inhibitor of testis-specific serine/threonine kinase 2 (TSSK2; IC50=31 nM) and focal adhesion kinase (FAK; IC50=2 nM) .
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Cat. No.: HY-13012G
CAS No.: 446859-33-2
Synonyms: E-616452 (GMP); SJN 2511 (GMP)
RepSox (E-616452) (GMP) is a RepSox (HY-13012) produced by using GMP guidelines. GMP small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. RepSox is a potent and selective TGF-β-RI/ALK5 inhibitor .
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Cat. No.: HY-10432G
CAS No.: 909910-43-6
A 83-01 (GMP) is A 83-01 (HY-10432) produced by using GMP guidelines. GMP small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. A 83-01 is a potent ALK4/5/7 inhibitor .
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Cat. No.: HY-19990
CAS No.: 1462949-64-9
Research Areas:  

Cancer

ALK kinase inhibitor-1 is an anaplastic lymphoma kinase (ALK) inhibitor extracted from patent US20130261106A1 compound I-202 .
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Cat. No.: HY-111752
CAS No.: 1373409-08-5
Purity:  98.02%
Research Areas:  

Cancer

EML4-ALK kinase inhibitor 1 is a potent orally active inhibitor of echinoderm microtubule-associated protein-like 4-anaplastic lymphoma kinase (EML4-ALK), with an IC50 of 1 nM .
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Cat. No.: HY-15656S
CAS No.: 1632484-77-5
Purity:  98.00%
Synonyms: LDK378 d7
Ceritinib (LDK378)-d7 is a deuterium labeled Ceritinib (HY-15656). Ceritinib is a selective, orally bioavailable and ATP-competitive ALK tyrosine kinase inhibitor . Ceritinib is a selective, orally bioavailable, and ATP-competitive ALK tyrosine kinase inhibitor with an IC50 of 200 pM. Ceritinib also inhibits IGF-1R, InsR, and STK22D with IC50 values of 8, 7, and 23 nM, respectively. Ceritinib shows great antitumor potency .
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Cat. No.: HY-111752R
CAS No.: 1373409-08-5
EML4-ALK Kinase inhibitor 1 (Standard) is the analytical standard of EML4-ALK Kinase inhibitor 1 (HY-111752). This product is intended for research and analytical applications. EML4-ALK Kinase inhibitor 1 is a potent orally active inhibitor of echinoderm microtubule-associated protein-like 4-anaplastic lymphoma Kinase (EML4-ALK), with an IC50 of 1 nM .
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Cat. No.: HY-159952
ALK5-IN-84 (Compound 23) is an ALK5 inhibitor with a pKi value of 9.35 against hALK5. When administered via inhalation, ALK5-IN-84 exhibits significant ALK5 inhibitory activity. ALK5-IN-84 is promising for the development of inhaled ALK5 inhibitors .
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