Based on 1 Customer Validation
A 83-01 (GMP) is A 83-01 (HY-10432) produced by using GMP guidelines. GMP small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. A 83-01 is a potent ALK4/5/7 inhibitor.
For research use only. We do not sell to patients.
- CAS No.: 909910-43-6
- Formula: C25H19N5S
- Molecular Weight:421.52
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
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SB-431542 (GMP)TGF-β Receptor Kinase Inhibitor -
HY-10182
LaduviglusibGSK-3 Inhibitor -
HY-10432
A 83-01ALK4/5/7 Inhibitor -
HY-12071G
LDN193189 (GMP)ALK2/3 Inhibitor -
HY-10431
SB-431542TGF-β Receptor Kinase Inhibitor -
HY-10254G
Mirdametinib (GMP)MEK Inhibitor -
HY-10432R
A 83-01 (Standard)ALK4/5/7 Inhibitor -
HY-10583
Y-27632 dihydrochlorideROCK Inhibitor -
HY-15659
Wnt-C59PORCN Inhibitor -
HY-12848
SAGSmoothened Agonist
Biological Activity
Description
In Vitro
A 83-01 (GMP) induces human foreskin fibroblasts converts into ardiomyocyte-like cells a more open-chromatin conformation at key heart developmental genes[1]. A 83-01 (GMP) induces cord blood or fetal liver-derived CD34+ cells converts into pluripotent cells[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. .
In Vivo
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 909910-43-6
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Appearance Solid
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Molecular Weight 421.52
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Formula C25H19N5S
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Color White to off-white
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SMILES
S=C(N1N=C(C2=NC(C)=CC=C2)C(C3=CC=NC4=CC=CC=C34)=C1)NC5=CC=CC=C5
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Shipping
Shipping with dry ice.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
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Data Sheet (275 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
[1]. Guan J, et al. Chemical reprogramming of human somatic cells to pluripotent stem cells. Nature. 2022 May;605(7909):325-331. [Content Brief]
[2]. Liu J, et al. Efficient episomal reprogramming of blood mononuclear cells and differentiation to hepatocytes with functional drug metabolism. Exp Cell Res. 2015 Nov 1;338(2):203-13. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
A 83-01 (GMP) Related Classifications
HY-10432G Related Classifications
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