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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
19 Results for "
ANOS1
" in MedChemExpress (MCE) Product Catalog:
Products (19)
19 Results for "ANOS1" in MCE Product Catalog:
6
6 Publications Verification
Synonyms: Endovion; NS3728
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Endovion is a pharmacological anion channel inhibitor (like chloride channel) and the specific VRAC/VSOAC blocker. Endovion (NS3728) is also an Anoctamin-1 (ANO 1) channel inhibitor [1] .
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3 Cited Publications
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T16Ainh-A01, an aminophenylthiazole, is a potent transmembrane protein 16A (TMEM16A) inhibitor, inhibiting TMEM16A-mediated chloride currents with an IC50 value of ~1 µM. TMEM16A (ANO1) functions as a calcium-activated chloride channel (CaCC) [1] .
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2 Cited Publications
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Ani9 is an ANO1 inhibitor, with an IC50 of 77 nM. Ani9 can inhibit smooth muscle contractions in mice and is applicable in research related to diseases such as tumors [1] .
2
2 Cited Publications
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ANO1-IN-1 (Compound 9c) is a selective ANO1 channel blocker with an IC50 of 2.56 μM and 15.43 μM against ANO1 and ANO2, respectively. ANO1-IN-1 suppresses strongly proliferation of glioblastoma cells [1].
1
1 Cited Publications
Cat. No.: HY-N5101
CAS No.: 36150-23-9
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1
1 Cited Publications
Cat. No.: HY-N4253
CAS No.: 173792-61-5
Cat. No.: HY-153508
CAS No.: 2098490-06-1
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ANO1-IN-4 (Compound 10bm) is a reversible inhibitor for calcium-activated chloride channel transmembrane protein 16A (TMEM16A, also known as ANO1) with an IC50 of 0.030 µM. ANO1-IN-4 exhibits good metabolic stability in rat liver microsomes. ANO1-IN-4 inhibits spontaneous contraction in mouse isolated ileum [1].
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DFBTA is an orally active and potent ANO1 (Calcium-activated chloride channel anoctamin-1) inhibitor, with an IC50 of 24 nM. DFBTA shows analgesic efficacy for inflammatory pain [1].
Cat. No.: HY-RS00750
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ANOS1 Human Pre-designed siRNA Set A contains three designed siRNAs for ANOS1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
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T16A(inh)-C01 is an inhibitor of TMEM16A (ANO1). T16A(inh)-C01 blocks chloride channel mediated by ANO1 with an IC50 of 8.4 μM, without interfering with calcium signaling [1].
Cat. No.: HY-175669
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ANO1-IN-5 is an orally active ANO1 inhibitor with an IC50 of 4.57 μM. J ANO1-IN-5 demonstrates 118-, 642-, and 10000-fold selectivity over α1A-,α1B-, andα1D-AR, respectively. ANO1-IN-5 exhibits significant inhibitory effects on osteoclast differentiation and function. ANO1-IN-5 can used for the study of osteoporosis [1].
Cat. No.: HY-147874
CAS No.: 2494280-04-3
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ANO1-IN-3 (Compound 3n) is a potent and selective ANO1 inhibitor with an IC50 of 1.23 μM. ANO1-IN-3 induces apoptosis [1].
Cat. No.: HY-146321
CAS No.: 637314-12-6
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ANO1-IN-2 (Compound 10q) is a selective ANO1 channel blocker with an IC50 of 1.75 μM and 7.43 μM against ANO1 and ANO2, respectively. ANO1-IN-2 suppresses strongly proliferation of glioblastoma cells [1].
Cat. No.: HY-P990337
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Cat. No.: HY-RS00740
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ANO1 Human Pre-designed siRNA Set A contains three designed siRNAs for ANO1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS23781
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Ano1 Rat Pre-designed siRNA Set A contains three designed siRNAs for Ano1 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS17326
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Ano1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Ano1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-105917R
CAS No.: 265646-85-3
Synonyms: Endovion (Standard); NS3728 (Standard)
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Research Areas:
Emidurdar (Standard) is the analytical standard of Emidurdar (HY-105917). This product is intended for research and analytical applications. Endovion is a pharmacological anion channel inhibitor (like chloride channel) and the specific VRAC/VSOAC blocker. Endovion (NS3728) is also an Anoctamin-1 (ANO 1) channel inhibitor [1] .
Cat. No.: HY-100612R
CAS No.: 552309-42-9
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T16Ainh-A01 (Standard) is the analytical standard of T16Ainh-A01 (HY-100612). This product is intended for research and analytical applications. T16Ainh-A01, an aminophenylthiazole, is a potent transmembrane protein 16A (TMEM16A) inhibitor, inhibiting TMEM16A-mediated chloride currents with an IC50 value of ~1 μM. TMEM16A (ANO1) functions as a calcium-activated chloride channel (CaCC) [1] .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
