173792-61-5
Chemical Structure
Kudinoside D
- CAS No.: 173792-61-5
- Formula:C47H72O17
- Molecular Weight:909.06
IUPAC Name: (1S,2S,4aR,6aS,6bR,10S,12aS)-1-hydroxy-10-(((2S,3R,4S,5S)-5-hydroxy-4-(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)-3-(((2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)tetrahydro-2H-pyran-2-yl)oxy)-1,2,6a,6b,9,9,12a-heptamethyl-1,3,4,5,6,6a,6b,7,8,8a,9,10,11,12,12a,12b-hexadecahydro-2H-2,4a-(epoxymethano)picen-15-one
InChIKey: ROLIIKCIEQNTMT-RWGSZDQYSA-N
SMILES: CC1([C@H](CC[C@]2(C1CC[C@@]3(C2C=CC4=C5[C@@](C(O6)=O)(CC[C@@]34C)CC[C@]6([C@@]5(C)O)C)C)C)O[C@H]7[C@@H]([C@H]([C@H](CO7)O)O[C@H]8[C@@H]([C@H]([C@@H]([C@H](O8)CO)O)O)O)O[C@H]9[C@@H]([C@@H]([C@H]([C@@H](O9)C)O)O)O)C
Biological Activity: Kudinoside D is a triterpenoid saponin. Kudinoside D is isolated from the leaves of Ilex kudingcha. Kudinoside D enhances the phosphorylation levels of AMPK and its downstream molecule ACC, and inhibits the expression of PPARγ, C/EBPα, SREBP-1c as well as the target genes of adipogenic transcription factors. Kudinoside D inhibits the activity of ANO1. Kudinoside D possesses hypolipidemic activity. Kudinoside D can be used in obesity-related research[1][2].
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Kudinoside D | 99.80% | Kudinoside D is a triterpenoid saponin. Kudinoside D is isolated from the leaves of Ilex kudingcha. Kudinoside D enhances the phosphorylation levels of AMPK and its downstream molecule ACC, and inhibits the expression of PPARγ, C/EBPα, SREBP-1c as well as the target genes of adipogenic transcription factors. Kudinoside D inhibits the activity of ANO1. Kudinoside D possesses hypolipidemic activity. Kudinoside D can be used in obesity-related research. | ||||||||||||||||||||
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- [1]. Che Y, et al. Kudinoside-D, a triterpenoid saponin derived from Ilex kudingcha suppresses adipogenesis through modulation of the AMPK pathway in 3T3-L1 adipocytes. Fitoterapia. 2018 Mar;125:208-216. [Content Brief]
- [2]. Mai NT, et al. Triterpenoid glycosides from the rhizomes of Allium ascalonicum and their anoctamin-1 inhibitory activity. Nat Prod Res. 2021 Nov;35(22):4338-4346. [Content Brief]
Keywords
