1. Membrane Transporter/Ion Channel
  2. Chloride Channel
  3. ANO1-IN-1

ANO1-IN-1 

Cat. No.: HY-146320
Handling Instructions

ANO1-IN-1 (Compound 9c) is a selective ANO1 channel blocker with an IC50 of 2.56 μM and 15.43 μM against ANO1 and ANO2, respectively. ANO1-IN-1 suppresses strongly proliferation of glioblastoma cells.

For research use only. We do not sell to patients.

ANO1-IN-1 Chemical Structure

ANO1-IN-1 Chemical Structure

CAS No. : 407587-01-3

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Description

ANO1-IN-1 (Compound 9c) is a selective ANO1 channel blocker with an IC50 of 2.56 μM and 15.43 μM against ANO1 and ANO2, respectively. ANO1-IN-1 suppresses strongly proliferation of glioblastoma cells[1].

IC50 & Target

IC50: 2.56 μM (ANO1), 15.43 μM (ANO2)[1]

In Vitro

ANO1-IN-1 (Compound 9c) (10 μM) significantly suppresses migration and invasion of U251 cells[1].
ANO1-IN-1 and TMZ combination brings about remarkable synergistic effects in suppressing proliferation of GBM cells[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

336.49

Formula

C18H28N2O2S

CAS No.
SMILES

CC(C)(C(NC1=C(C2=C(S1)CC(CC2)C(C)(C)C)C(N)=O)=O)C

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
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ANO1-IN-1
Cat. No.:
HY-146320
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