36150-23-9
36150-23-9
Chemical Structure
Kobusin
- CAS No.: 36150-23-9
- Formula:C21H22O6
- Molecular Weight:370.40
IUPAC Name: 5-((1S,3aR,4S,6aR)-4-(3,4-dimethoxyphenyl)tetrahydro-1H,3H-furo[3,4-c]furan-1-yl)benzo[d][1,3]dioxole
InChIKey: AWOGQCSIVCQXBT-VUEDXXQZSA-N
SMILES: COC1=CC=C([C@H]2OC[C@]3([H])[C@@H](C4=CC=C(OCO5)C5=C4)OC[C@@]32[H])C=C1OC
Biological Activity: Kobusin is a bisepoxylignan isolated from the Pnonobio biondii Pamp. Kobusin is an activator of CFTR and CaCCgie chloride channels and a inhibitor of ANO1/CaCC (calcium-activated chloride channel) channel[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Kobusin | 99.61% | Kobusin is a bisepoxylignan isolated from the Pnonobio biondii Pamp. Kobusin is an activator of CFTR and CaCCgie chloride channels and a inhibitor of ANO1/CaCC (calcium-activated chloride channel) channel. | ||||||||||||||||||||
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References
- [1]. Yu Jiang , et al. Modulation of Chloride Channel Functions by the Plant Lignan Compounds Kobusin and Eudesmin. Front Plant Sci. 2015 Nov 25;6:1041. [Content Brief]
- [2]. Xing Zhang, et al. Bioassay-guided isolation of bisepoxylignans from the flower buds of Magnolia biondii Pamp and their antiallergic effects. RSC Adv., 2017,7, 34236-34243.
