3 Results for "

Actinonin

" in MedChemExpress (MCE) Product Catalog:
Products (3)

3 Results for "Actinonin" in MCE Product Catalog:

7
Actinonin
Actinonin
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7 Cited Publications
Cat. No.: HY-113952
CAS No.: 13434-13-4
Purity:  98.37%
Synonyms: (-)-Actinonin
Category:  

Infection Natural Products Microorganisms Marine natural products Disease Research Fields

Target:  

Aminopeptidase Bacterial MMP Apoptosis Antibiotic

Actinonin ((-)-Actinonin) is a naturally occurring antibacterial agent produced by Actinomyces. Actinonin inhibits aminopeptidase M, aminopeptidase N and leucine aminopeptidase. Actinonin is a potent reversible peptide deformylase (PDF) inhibitor with a Ki of 0.28 nM. Actinonin also inhibits MMP-1, MMP-3, MMP-8, MMP-9, and hmeprin α with Ki values of 300 nM, 1,700 nM, 190 nM, 330 nM, and 20 nM, respectively. Actinonin is an apoptosis inducer. Actinonin has antiproliferative and antitumor activities .
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Suc-Ala-Ala-Pro-Leu-pNA
Suc-Ala-Ala-Pro-Leu-pNA
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Cat. No.: HY-P2648
CAS No.: 70968-04-6
Synonyms: N-Succinyl-AAPL-p-nitroanilide
Target:  

Aminopeptidase

Research Areas:  

Endocrinology

Suc-Ala-Ala-Pro-Leu-pNA (N-Succinyl-AAPL-p-nitroanilide) is a tripeptidyl p-nitroanilide substrate that can be catalytically hydrolyzed by acyl amidase-like leucine aminopeptidase in seminal plasma. Amastatin (HY-129298) and Actinonin (HY-113952) exert potent inhibitory effects on this hydrolytic activity. Suc-Ala-Ala-Pro-Leu-pNA can be used for the research of diseases such as azoospermia .
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Actinonin (Standard)
Actinonin (Standard)
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Cat. No.: HY-113952R
CAS No.: 13434-13-4
Synonyms: (-)-Actinonin (Standard)
Category:  

Natural Products Microorganisms

Target:  

Reference Standards Aminopeptidase Bacterial MMP Apoptosis Antibiotic

Actinonin (Standard) is the analytical standard of Actinonin. This product is intended for research and analytical applications. Actinonin ((-)-Actinonin) is a naturally occurring antibacterial agent produced by Actinomyces. Actinonin inhibits aminopeptidase M, aminopeptidase N and leucine aminopeptidase. Actinonin is a potent reversible peptide deformylase (PDF) inhibitor with a Ki of 0.28 nM. Actinonin also inhibits MMP-1, MMP-3, MMP-8, MMP-9, and hmeprin α with Ki values of 300 nM, 1,700 nM, 190 nM, 330 nM, and 20 nM, respectively. Actinonin is an apoptosis inducer. Actinonin has antiproliferative and antitumor activities[1][2][3][4][5].
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