1 Result for "

Arf1-GEFs-IN-1

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "Arf1-GEFs-IN-1" in MCE Product Catalog:

Cat. No.: HY-175290
CAS No.: 3091068-95-7
Target:  

Arf Family GTPase

Research Areas:  

Cancer

Arf1-GEFs-IN-1 is a potent and orally active ADP-ribosylation factor 1- guanine nucleotide exchange factors (Arf1-GEFs) inhibitor with an IC50 value of 40.85 μM against CT26 cells. Arf1-GEFs-IN-1 primarily mediates tumor regression by triggering anti-tumor immune responses, rather than through direct cytotoxicity. Arf1-GEFs-IN-1 effectively promotes CCL5 expression, demonstrates excellent in vivo efficacy. Arf1-GEFs-IN-1 can be used for the study of colon cancer .
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