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Results for "

BMS-354825 (GMP)

" in MedChemExpress (MCE) Product Catalog:

2

Inhibitors & Agonists

1

Fluorescent Dyes

1

Biochemical Assay Reagents

2

GMP Molecules

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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-10181G

    BMS-354825 (GMP)

    Src Bcr-Abl Apoptosis Autophagy Cancer
    Dasatinib (BMS-354825) (GMP) is a GMP-grade Dasatinib (HY-10181). GMP-grade small molecules can be used as adjuvant agents in cell therapy. Dasatinib (BMS-354825) is an orally active, ATP-competitive, dual Src/Bcr-Abl inhibitor with potent antitumor activity. The Ki values ​​for Src and Bcr-Abl are 16 pM and 30 pM, respectively. Dasatinib inhibits Bcr-Abl and Src with IC50 values ​​of less than 1.0 nM and 0.5 nM, respectively. Dasatinib also induces apoptosis and autophagy .
    Dasatinib (GMP)
  • HY-10181GL

    BMS-354825 (GMP Like)

    Bcr-Abl Src Autophagy Apoptosis Cancer
    Dasatinib (GMP Like) (BMS-354825 (GMP Like)) is Dasatinib (HY-10181) produced by using GMP like guidelines. GMP Like small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. Dasatinib (BMS-354825) is a highly potent, ATP competitive, orally active dual Src/Bcr-Abl inhibitor with potent antitumor activity. The Kis are 16 pM and 30 pM for Src and Bcr-Abl, respectively. Dasatinib inhibits Bcr-Abl and Src with IC50s of <1.0 nM and 0.5 nM, respectively . Dasatinib also induces apoptosis and autophagy.
    Dasatinib (GMP Like)

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