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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
18 Results for "
Bedaquiline
" in MedChemExpress (MCE) Product Catalog:
Products (18)
18 Results for "Bedaquiline" in MCE Product Catalog:
56
56 Publications Verification
Synonyms: TMC207; R207910
Target:
Research Areas:
Bedaquiline (TMC207) is a diarylquinoline agent and inhibits Mycobacterium tuberculosis (Mtb) F1FO-ATP synthase through targeting of both the c- and the ε-subunit . Bedaquiline has uncoupler activity. Bedaquiline is used for the multi-agent resistant tuberculosis .
56
56 Publications Verification
Synonyms: R403323; TMC207 fumarate; R207910 fumarate
Target:
Research Areas:
Bedaquiline fumarate, a diarylquinoline antibiotic that targets ATP synthase, is effective for the treatment of Mycobacterium tuberculosis infections.
1
1 Cited Publications
Cat. No.: HY-19750
CAS No.: 1494675-86-3
TBA-7371 is an orally active and non-covalent inhibitor of Decaprenylphosphoryl-β-D-ribose oxidase (DprE1) of Mycobacterium tuberculosis (MIC=0.64 μg/mL). TBA-7371 can block the synthesis of arabinose in the bacterial cell wall, resulting in cell wall structural defects, thereby exerting an anti-tuberculosis effect. TBA-7371 can be used in the research of anti-tuberculosis drugs and has a synergistic bactericidal effect with Bedaquiline (HY-14881) and other drugs .
Cat. No.: HY-14881AR
CAS No.: 845533-86-0
Synonyms: R403323 (Standard); TMC207 fumarate (Standard); R207910 fumarate (Standard)
Target:
Research Areas:
Bedaquiline (fumarate) (Standard) is the analytical standard of Bedaquiline (fumarate). This product is intended for research and analytical applications. Bedaquiline fumarate, a diarylquinoline antibiotic that targets ATP synthase, is effective for the treatment of Mycobacterium tuberculosis infections.
Cat. No.: HY-14881R
CAS No.: 843663-66-1
Synonyms: TMC207 (Standard); R207910 (Standard)
Target:
Research Areas:
Bedaquiline (Standard) is the analytical standard of Bedaquiline. This product is intended for research and analytical applications. Bedaquiline (TMC207) is a diarylquinoline agent and inhibits Mycobacterium tuberculosis (Mtb) F1FO-ATP synthase through targeting of both the c- and the ε-subunit . Bedaquiline has uncoupler activity. Bedaquiline is used for the multi-agent resistant tuberculosis .
(Rac)-TBAJ-876 is a racemate of TBAJ-876. TBAJ-876 is the inhibitor of mycobacterium tuberculosis. TBAJ-876 is the analogue of the anti-tuberculosis agent Bedaquiline (HY-14881). TBAJ-876 has the potential for the research of tuberculosis .
Cat. No.: HY-14881C
CAS No.: 857086-93-2
Synonyms: (1S,2R)-TMC207; (1S,2R)-R207910
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Research Areas:
(1S,2R)-Bedaquiline ((1S,2R)-TMC207) is a drug intermediate for synthesis of various active compounds.
Cat. No.: HY-32956
CAS No.: 163105-90-6
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Research Areas:
2-Methoxypyridine-3-boronic acid is a pyridine boronic acid compound and also borylation reagent used in Suzuki cross-coupling reactions .
Cat. No.: HY-14881B
CAS No.: 654655-80-8
Synonyms: (Rac)-TMC207; (Rac)-R207910
(Rac)-Bedaquiline is the racemate of Bedaquiline. Bedaquiline (TMC207) is a diarylquinoline agent and inhibits Mycobacterium tuberculosis (Mtb) F1FO-ATP synthase through targeting both the c- and the ε-subunit. Bedaquiline has uncoupler activity. Bedaquiline is used for the multi-agent resistant tuberculosis .
Cat. No.: HY-170472
CAS No.: 2375174-10-8
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Research Areas:
Bpin-Bedaquiline (compound 2) is a boronic ester precursor of Bedaquiline (HY-14881). Bpin-Bedaquiline can react with H476Br to synthesize 76Br-Bedaquiline .
Cat. No.: HY-14881S2
Cat. No.: HY-W753222
Synonyms: Bedaquiline fumarate impurity 8-d6
Cat. No.: HY-158380
CAS No.: 3125917-86-1
UH-NIP-16 exhibits antimicrobial activity against Mycobacterium tuberculosis, with MIC50 of 1.86 and 3.05 μM, for pathogenic mycobacterial strains H37Rv and CDC1551. UH-NIP-16 synergizes with Streptomycin (HY-B1906), Isoniazid (HY-B0329), Ethambutol (HY-B0535) and Bedaquiline (HY-14881), potentiates their anti-tuberculosis activities .
Cat. No.: HY-14881CR
CAS No.: 857086-93-2
Synonyms: (1S,2R)-TMC207 (Standard); (1S,2R)-R207910 (Standard)
Target:
(1S,2R)-Bedaquiline (Standard) is the analytical standard of (1S,2R)-Bedaquiline. This product is intended for research and analytical applications.
Cat. No.: HY-183551
Antitubercular agent-59 is an orally active antitubercular agent with an IC50 of 51 nM against Mycobacterium tuberculosis H37Rv. Antitubercular agent-59 inhibits growth of Bedaquiline (HY-14881)-resistant Rv0678G12C mutant strains. Antitubercular agent-59 exerts bactericidal activity in chronic tuberculosis mouse models with 1-Aminobenzotriazole (HY-103389) coadministration .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
