2 Results for "

Bicuculline (Standard)

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "Bicuculline (Standard)" in MCE Product Catalog:

Cat. No.: HY-N0219R
CAS No.: 485-49-4
Synonyms: (+)-Bicuculline (Standard)
Bicuculline (Standard) is the analytical standard of Bicuculline. This product is intended for research and analytical applications. Bicuculline ((+)-Bicuculline) is A competing neurotransmitter GABAA receptor antagonist (IC50=2 μM). Bicuculline also blocks Ca2+ activating potassium (SK) channels and subsequently blocks slow post-hyperpolarization (slow AHP). Bicuculline has anticonvulsant activity. Bicuculline can be used to induce seizures in mice .
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Cat. No.: HY-103474R
CAS No.: 40709-69-1
Synonyms: (-)-Bicuculline methiodide (Standard)
Research Areas:  

Neurological Disease

Bicuculline methiodide (Standard) is the analytical standard of Bicuculline methiodide (HY-103474). This product is intended for research and analytical applications. Bicuculline methiodide ((-)-Bicuculline methiodide) is a potent GABAA blocker. Bicuculline methiodide alters membrane properties and firing pattern. Bicuculline methiodide reduces the Apamin-sensitive afterhyperpolarization, while Apamin is a toxin isolated from bee venom to block small conductance Ca2+ -activated K+ channels. Bicuculline methiodide facilitates burst firing via blocking apamin-sensitive Ca2+ -activated K+ current .
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