1 Result for "

Biotinyl-Amylin (human)

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "Biotinyl-Amylin (human)" in MCE Product Catalog:

Biotinyl-Amylin (human)
Biotinyl-Amylin (human)
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Cat. No.: HY-P4863
CAS No.: 1678415-18-3
Target:  

CGRP Receptor

Research Areas:  

Neurological Disease Metabolic Disease

Biotinyl-Amylin (human) is a biotin-labeled derivative of Amylin, amide, human (HY-P1070). Biotinyl-Amylin (human) acts as a competitive agonist for the Calcitonin Receptor (CTR) and for the Amylin receptors (AMY1, AMY2, and AMY3) formed by the association of CTR with RAMP1/2/3. By mimicking endogenous human amylin, Biotinyl-Amylin (human) binds to and activates CTR and AMY receptors, thereby initiating downstream signaling pathways involving cAMP, CREB, and ERK1/2, while retaining high-affinity receptor binding and activation capabilities. Biotinyl-Amylin (human) is primarily utilized in studies investigating the metabolic regulatory mechanisms underlying obesity and diabetes; it is also applicable to pharmacological research, receptor localization studies, and ligand-binding assays related to Amylin receptors in the context of Alzheimer's disease .
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