1 Result for "

Bortezomib-d8

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "Bortezomib-d8" in MCE Product Catalog:

Cat. No.: HY-10227S
Purity:  ≥98.0%
Synonyms: PS-341-d8; LDP-341-d8; NSC 681239-d8
Bortezomib-d8 is the deuterium labeled Bortezomib. Bortezomib (PS-341) is a reversible and selective proteasome inhibitor, and potently inhibits 20S proteasome (Ki=0.6 nM) by targeting a threonine residue. Bortezomib disrupts the cell cycle, induces apoptosis, and inhibits NF-κB. Bortezomib is the first proteasome inhibitor anticancer agent. Bortezomib can be used for the study of multiple myeloma (MM) . Bortezomib effectively inhibits TREM2 expression in tumor-associated macrophages (TAMs) .
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