301 Results for "

C12

" in MedChemExpress (MCE) Product Catalog:
Products (301)

301 Results for "C12" in MCE Product Catalog:

28
28 Publications Verification
Cat. No.: HY-N0155
CAS No.: 478-01-3
Nobiletin is a poly-methoxylated flavone from the citrus peel that improves memory loss. Nobiletin is a retinoid acid receptor-related orphan receptors (RORs) agonist. Nobiletin can reduce reactive oxygen species (ROS) levels in differentiated C2C12 myotubes and has anti-inflammation and anti-cancer properties, including anti-angiogenesis, anti-proliferation, anti-metastasis and induced apoptosis .
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20
20 Cited Publications
Cat. No.: HY-145405
CAS No.: 1220890-25-4
Purity:  99.91%
C12-200 is a type of ionizable cationic lipid and helper lipid commonly used for mRNA delivery. In the hemophilia B mouse model, mRNA encoding human erythropoietin (EPO) and coagulation factor IX (FIX) can be successfully delivered and expressed using C12-200. C12-200 is utilized in research related to hemophilia B .
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12
12 Cited Publications
Cat. No.: HY-113071A
CAS No.: 2618458-93-6
Purity:  ≥98.0%
Synonyms: MVA lithium salt
Mevalonic acid (MVA) lithium salt is a precursor substance of the mevalonate pathway, which is essential for cell growth and proliferation. Mevalonic acid lithium salt is effective in inhibiting Simvastatin (HY-17502)-induced decrease in C2C12 cell viability in vitro. Mevalonic acid lithium salt can be used in studies of myopathy and heart failure .
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11
11 Cited Publications
Cat. No.: HY-126839
CAS No.: 138777-25-0
Purity:  99.82%
Synonyms: 5-Dodecanoylaminofluorescein di-β-D-Galactopyranoside
C12FDG (5-Dodecanoylaminofluorescein di-β-D-Galactopyranoside) is a lipophilic green fluorescent substrate for β-galactosidase detection. C12-FDG is more sensitive than Fluorescein di(β-D-galactopyranoside) (HY-101895) for beta-galactosidase activity determinations in animal cells (Ex/Em = 488/523 nm) .
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5
5 Cited Publications
Cat. No.: HY-138226
CAS No.: 158757-84-7
Purity:  98.42%
BODIPY 558/568 C12 is a BODIPY dye. BODIPY dye is a small molecule dye with strong ultraviolet absorption ability, its fluorescence peak is relatively sharp, and the quantum yield is high. They are relatively insensitive to the polarity and pH of the environment and are relatively stable under different physiological conditions. Due to its structural asymmetry, BODIPY derives a variety of structural products. BODIPY lipid droplet dyes can well pass through the cell membrane into the cell, and localize the neutral lipids in the cell to specifically stain the lipid droplets, which can be used for labeling of live cells and fixed cells . Maximum excitation/emission wavelength: 558/568 nm .
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4
4 Cited Publications
Cat. No.: HY-112821
CAS No.: 385425-03-6
Purity:  98.22%
Target:  

YAP

Research Areas:  

Inflammation/Immunology

IBS008738 is a potent TAZ activator. IBS008738 stabilizes TAZ, increases the unphosphorylated TAZ level, enhances the association of MyoD with the myogenin promoter, upregulates MyoD-dependent gene transcription, and competes with myostatin in C2C12 cells. IBS008738 enhances myogenesis in C2C12 cells and facilitates muscle repair in a muscle injury model .
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2
2 Cited Publications
Cat. No.: HY-114544A
CAS No.: 168982-69-2
Purity:  ≥98.0%
Synonyms: OdDHL
N-3-oxo-dodecanoyl-L-Homoserine lactone (3-oxo-C12-HSL) is a bacterial quorum-sensing signaling molecule produced by P. aeruginosa and strains of the B. cepacia complex .Quorum sensing is a regulatory system used by bacteria for controlling gene expression in response to increasing cell density.N-3-oxo-dodecanoyl-L-Homoserine lactone induces the production of IL-8 in 16HBE human bronchial epithelial cells .
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2
2 Cited Publications
Cat. No.: HY-D1617
CAS No.: 144672-74-2
BODIPY 500/510 C1, C12 is a BODIPY dye. BODIPY dye is a small molecule dye with strong ultraviolet absorption ability, its fluorescence peak is relatively sharp, and the quantum yield is high. They are relatively insensitive to the polarity and pH of the environment and are relatively stable under different physiological conditions. Due to its structural asymmetry, BODIPY derives a variety of structural products. BODIPY lipid droplet dyes can well pass through the cell membrane into the cell, and localize the neutral lipids in the cell to specifically stain the lipid droplets, which can be used for labeling of live cells and fixed cells . Maximum excitation/emission wavelength: 500/510 nm . Protect from light, stored at -20°C.
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2
2 Cited Publications
Cat. No.: HY-128591
CAS No.: 1269365-82-3
Purity:  98.70%
Target:  

Phosphatase

Research Areas:  

Metabolic Disease

DIPQUO is an activator of the bone marker alkaline phosphatase (ALP), with an EC50 of 6.27 μM in C2C12 cells. DIPQUO promotes mouse and human osteoblast differentiation via activation of p38 MAPK-β .
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2
2 Cited Publications
Cat. No.: HY-112820
CAS No.: 500008-45-7
Purity:  98.06%
Research Areas:  

Others

Chlorantraniliprole is an insecticide that potently and selectively activates insect ryanodine receptor, with EC50s of 40 nM and 50 nM for Drosophila melanogaster and H. virescens ryanodine receptor, and ~300-fold more potent than that in the mouse myoblast cell line, C2C12 (EC50, 14 μM).
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2
2 Cited Publications
Cat. No.: HY-P80179
Synonyms: H4/A, H4FA, HIST1H4A, H4C2, H4/I, H4FI, HIST1H4B, H4C3, H4/G, H4FG, HIST1H4C, H4C4, H4/B, H4FB, HIST1H4D, H4C5, H4/J, H4FJ, HIST1H4E, H4C6, H4/C, H4FC, HIST1H4F, H4C8, H4/H, H4FH, HIST1H4H, H4C9, H4/M, H4FM, HIST1H4I, H4C11, H4/E, H4FE, HIST1H4J, H4C12, H4/D, H4FD, HIST1H4K, H4C13, H4/K, H4FK, HIST1H4L, H4C14, H4/N, H4F2, H4FN, HIST2H4, HIST2H4A, H4C15, H4/O, H4FO, HIST2H4B, H4C16, H4-16, HIST4H4, H4C1, Histone H4, H4K5ac

Host:  

Rabbit

Application:  

WB, IHC-P, FC, ICC/IF

Reactivity:  

Human, Mouse, Rat

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1
1 Cited Publications
Cat. No.: HY-138941
CAS No.: 3055-98-9
Purity:  ≥98.0%
Synonyms: C12E8
Target:  

Influenza Virus

Research Areas:  

Infection

Octaethylene glycol monododecyl ether (C12E8) is an non-ionic detergent that can be used for membrane protein extraction. Octaethylene glycol monododecyl ether can solubilize the viral membrane of intact influenza virus .
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1
1 Cited Publications
Cat. No.: HY-D1553
CAS No.: 1029138-21-3
BODIPY-C12 is a boron-dipyrromethene derivative containing a lipophilic tail (excitation 490 nm). BODIPY-C12 is a hydrophobic molecular and sensitivity to the surrounding environment and can be used to quantify viscosity, critical micelle concentration, and critical micelle temperature .
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1
1 Cited Publications
Cat. No.: HY-118697
CAS No.: 137173-46-7
Purity:  ≥98.0%
Synonyms: C12-HSL
Target:  

Bacterial

Research Areas:  

Infection

N-dodecanoyl-L-Homoserine lactone (C12-HSL) is a quorum sensing (QS) signaling molecule. N-dodecanoyl-L-Homoserine lactone (C12-HSL) aptamers blocks qurom sensing and inhibits biofilm formation in Pseudomonas aeruginosa .
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1
1 Cited Publications
Cat. No.: HY-148859
CAS No.: 2938207-23-7
Purity:  ≥98.0%
AA-T3A-C12 is an anisamide ligand-tethered lipidoid (AA-lipidoid). AA-T3A-C12 mediates great RNA delivery and transfection of activated fibroblasts .
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1
1 Cited Publications
Cat. No.: HY-100353
CAS No.: 74713-60-3
Purity:  99.82%
Synonyms: N-Lauroyl-D-erythro-sphingosine; N-Laurylsphingosine
Target:  

Endogenous Metabolite

Research Areas:  

Metabolic Disease Cancer

C12-Ceramide (N-Lauroyl-D-erythro-sphingosine), a naturally occurring ceramide, is formed by hydrolysis of C12 sphingomyelin. C12-Ceramide can enhance the Doxorubicin toxicity in MDA-MB-231 cells. C12-Ceramide also can be used to diagnose types A and B Niemann-Pick disease .
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1
1 Cited Publications
Cat. No.: HY-P5524A
Synonyms: Lauroyl-γ-D-glutamyl-meso-diaminopimelic acid hydrochloride; γ-D-glutamyl-meso-diaminopimelic acid hydrochloride
Research Areas:  

Others

C12-iE-DAP hydrochloride is the hydrochloride salt form of C12-iE-DAP (HY-P5524). C12-iE-DAP hydrochloride is a biologically active peptide that has agonistic effects on NOD1 .
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1
1 Cited Publications
Cat. No.: HY-P1592
CAS No.: 848301-94-0
Target:  

Galectin

Research Areas:  

Cancer

G3-C12 is a galectin-3 binding peptide, with Kd of 88 nM, and shows anticancer activity.
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1
1 Cited Publications
Cat. No.: HY-139407
CAS No.: 1246303-05-8
Synonyms: 3-Dodecanoyl-NBD-cholesterol
Target:  

Fluorescent Dye

Research Areas:  

Others

3-C12-NBD-cholesterol is a fluorescent cholesterol analog that can be used for measuring membrane and intracellular trafficking dynamics .
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1
1 Cited Publications
Cat. No.: HY-P1592A
Target:  

Galectin

Research Areas:  

Cancer

G3-C12 (TFA) is a galectin-3 binding peptide, with Kd of 88 nM, and shows anticancer activity.
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