1 Result for "

C5aR1 antagonist 2

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "C5aR1 antagonist 2" in MCE Product Catalog:

Cat. No.: HY-163379
CAS No.: 2365161-92-6
Target:  

Complement System

Research Areas:  

Inflammation/Immunology

C5aR1 antagonist 2 (Compound 6a) is an orally active C5a receptor 1 (C5aR1) antagonist that shows efficacy in inhibiting the C5a-induced neutrophil count increase. C5aR1 antagonist 2 is potent in the DISCO and migration assays, with IC50 values of 21 and 3 nM, respectively. C5aR1 antagonist 2 can be used for the research of acute and chronic inflammatory diseases .
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