1 Result for "

CB 3703

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "CB 3703" in MCE Product Catalog:

Cat. No.: HY-119143
CAS No.: 32093-09-7
CB 3703 is an inhibitor of thymidylate synthase (TS) and dihydrofolate reductase (DHFR). CB 3703 has an IC50 of 0.25 μM against rat TS, a Ki of 0.47 μM against mouse TS, an IC50 of 6.8 nM against rat DHFR, and a Ki of 0.6 pM against mouse DHFR. CB 3703 is transported via the reduced folate pathway, has a short plasma half-life, and can prolong the survival of tumor-bearing mice. CB 3703 can be used in the research of L1210 ascites tumors .
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