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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
17 Results for "
CK-19
" in MedChemExpress (MCE) Product Catalog:
Products (17)
17 Results for "CK-19" in MCE Product Catalog:
1
Research Areas:
Levobunolol (l-Bunolol) hydrochloride is a non-selective β-adrenergic antagonist and vasodilator. By blocking calcium ion influx and reducing the sensitivity of vascular smooth muscle to calcium, Levobunolol hydrochloride effectively dilates the ciliary arteries and increases ocular blood flow, so it is widely used in research on glaucoma and ocular hypertension. Levobunolol hydrochloride inhibits the β-receptor signaling pathway and the expression of related proliferation markers (such as CK3, CK14, CK19, Ki67) in corneal cells. In rabbit models, Levobunolol hydrochloride not only does not inhibit corneal epithelial regeneration, but also accelerates the healing of mechanical injury without adverse effects. Levobunolol hydrochloride also inhibits histamine-induced vasoconstriction and intracellular calcium elevation, exhibiting unique vascular regulatory activity. Levobunolol hydrochloride protects ocular blood flow and promotes corneal repair .
1
Cat. No.: HY-169004
CAS No.: 1623794-90-0
Target:
Research Areas:
CBT-295 is an orally active autotaxin (ATX) inhibitor. CBT-295 exhibits a significant reduction in inflammatory cytokines like TGF-β, TNF-α and IL-6 levels, also reduced bile duct proliferation marker CK-19 and lowered liver fibrosis. The reversal of liver fibrosis with CBT-295 led to a reduction in blood and brain ammonia levels. CBT-295 also reduced neuroinflammation induced by ammonia. CBT-295 is promising for research of liver cirrhosis and associated encephalopathy .
Cat. No.: HY-P81183A
Synonyms: 40 kDa keratin intermediate filament; CK 19; CK19; CK19; CK-19; KRT19; Cytokeratin19; Cytokeratin-19; k19; k1cs; Keratin 19; Keratin-19; Keratin type I 40 kD; Keratin type i 40kD; Keratin type I cytoskeletal 19; krt19; mgc15366; K1C19_HUMAN; Keratin, type I cytoskeletal 19; Keratin, type I, 40 kd.
Cat. No.: HY-P81250
Synonyms: 40 kDa keratin intermediate filament; CK 19; CK19; CK19; CK-19; KRT19; Cytokeratin19; Cytokeratin-19; k19; k1cs; Keratin 19; Keratin-19; Keratin type I 40 kD; Keratin type i 40kD; Keratin type I cytoskeletal 19; krt19; mgc15366; K1C19_HUMAN; Keratin, type I cytoskeletal 19; Keratin, type I, 40 kd
Cat. No.: HY-B1035A
CAS No.: 47141-42-4
Synonyms: l-Bunolol
Research Areas:
Levobunolol (l-Bunolol) is a non-selective β-adrenergic antagonist and vasodilator. By blocking calcium ion influx and reducing the sensitivity of vascular smooth muscle to calcium, Levobunolol effectively dilates the ciliary arteries and increases ocular blood flow, so it is widely used in research on glaucoma and ocular hypertension. Levobunolol inhibits the β-receptor signaling pathway and the expression of related proliferation markers (such as CK3, CK14, CK19, Ki67) in corneal cells. In rabbit models, Levobunolol not only does not inhibit corneal epithelial regeneration, but also accelerates the healing of mechanical injury without adverse effects. Levobunolol also inhibits histamine-induced vasoconstriction and intracellular calcium elevation, exhibiting unique vascular regulatory activity. Levobunolol protects ocular blood flow and promotes corneal repair .
Cat. No.: HY-P85943
Synonyms: 40 kDa keRatin intermediate filament; CK 19; CK-19; CK19; Cytokeratin 19; CytokeRatin-19; K19; K1C19_HUMAN; K1CS; KeRatin 19; KeRatin type I 40 kD; KeRatin type I 40kD; KeRatin type I cytoskeletal 19; KeRatin, type I cytoskeletal 19; KeRatin, type I, 40 kd; KeRatin-19; KRT19; MGC15366
Cat. No.: HY-P700770
Purity: ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: KRT19; Keratin, Type I, 40-Kd; Keratin 19; Keratin 19, Type I; Keratin, Type I Cytoskeletal 19; Cytokeratin 19; K19; Cytokeratin-19; CK19; Keratin-19; K1CS; MGC15366; 40-KDa Keratin Intermediate Filament; CK-19
Species:
Canine
Source:
E. coli
Cat. No.: HY-P81183
Synonyms: 40 kDa keratin intermediate filament; CK 19; CK19; CK19; CK-19; KRT19; Cytokeratin19; Cytokeratin-19; k19; k1cs; Keratin 19; Keratin-19; Keratin type I 40 kD; Keratin type i 40kD; Keratin type I cytoskeletal 19; krt19; mgc15366; K1C19_HUMAN; Keratin, type I cytoskeletal 19; Keratin, type I, 40 kd.
Cat. No.: HY-RS07442
Target:
Research Areas:
KRT19 Human Pre-designed siRNA Set A contains three designed siRNAs for KRT19 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS16276
Target:
Research Areas:
Krt19 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Krt19 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
