Cytokeratin 19 Antibody (YA6147)
(Synonyms: KRT19; Keratin, type I cytoskeletal 19; Cytokeratin-19; CK-19; Keratin-19; K19)Cytokeratin 19 Antibody (YA6147) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Cytokeratin 19.
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Host:
Rabbit
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Isotype:
IgG
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Application:
WB, IHC-P, ICC/IF, FC, IF-Tissue, mIHC
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Reactivity :
Human, Mouse, Rat
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Formulation:
Supplied in 1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
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Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
WB
WB: Western Blot
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ICC/IF
ICC/IF: Immunocytochemistry/
Immunofluorescence |
IF-Tissue
IF-Tissue: Immunofluorescence-Tissue
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IHC-P
IHC-P: Immunohistochemistry-Paraffin
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FC
FC: Flow Cytometry
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mIHC
mIHC: Multiplex Immunohistochemical
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|---|---|---|---|---|---|---|
| Dilution Ratio | 1:2,000-1:5,000 | 1:500 | 1:500 | 1:1,000 | 1:1,000 | 1:2,000-1:10,000 |
Product Details
Cytokeratin 19 Antibody (YA6147) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Cytokeratin 19.
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Host Rabbit
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Clonality Monoclonal
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Species ReactivityHuman, Mouse, Rat
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Observed Molecular WeightObserved band size: 44 kDa
Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
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Calculated Molecular Weight Predicted band size: 44 kDa
Synthetic peptide within Human Cytokeratin 19 aa 348-400 / 400.
Protein A
Non-conjugated
Unmodified
IgG
Product Properties
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Appearance
Liquid
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Formulation
Supplied in 1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
Cytokeratin 19 is involved in the organization of myofibers. Together with KRT8, helps to link the contractile apparatus to dystrophin at the costameres of striated muscle
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Expression
Tissue_specificity:It is expressed in specific basal keratinocyte regions of the deep outer root sheath of hair follicles. It is also found in sweat glands and mammary ducts and secretory cells, bile ducts, gastrointestinal tract, bladder urothelial tissue, oral epithelium, esophagus, and cervical external epithelium (protein level) . It is expressed in specific regions of epidermal basal cells, nipple epidermis, and hair follicles. It is also found in some wall cells of the human umbilical vein and arteries, as well as in the smooth muscle of umbilical vessels. In structures containing dystrophin and spectroscopylin, muscle fibers aggregate in sarcomeres within the sarcoplasm of the sarcolemma. -
Subunit
Heterotetramer of two type I and two type II keratins. Interacts with PNN and the actin-binding domain of DMD. Interacts with HCV core protein
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SwissProt ID
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Synonyms
KRT19; Keratin, type I cytoskeletal 19; Cytokeratin-19; CK-19; Keratin-19; K19
Documentation
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